Doctoral Student

Mari Niemelä

Hot melt extrusion for drug manufacturing

>> 2022- 2025

Mari Niemelä_edited.jpg

Hot melt extrusion is a manufacturing method used in pharmaceutical industry to improve the absorption of poorly soluble drug molecules.

 

In this project, the areas of interests include for example investigating the state of drug molecules in the polymer matrix and maintaining them in molecularly dispersed or amorphous state in the final product, investigating and modelling the effect of the drug molecule on the behavior of the melt flow during processing and defining the suitable combination of drug molecules and polymer matrix.  

Industry Partner

Jorma Roine 

Bayer

Johanna Aho

Bayer

Academic Supervisor

Minna Kellomäki

TAU

 

 

Mikko Kanerva

TAU