Enteropathies including celiac disease can affect the function of the small intestine. These enteropathies may result in damage to the brush border membrane of small intestine, potentially affecting the production of crucial enzymes needed to degrade nutrients into absorbable sizes.

A central goal of this project is to develop robust models of enteropathy that allow for real-time absorption and digestion analyses. A key outcome will be the generation of tools for high-throughput screening of candidate supplements or therapeutics targeting the small intestine, to assess how novel therapies can improve digestive health.